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KMID : 0363220140520020133
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Korean Journal of Dermatology
2014 Volume.52 No. 2 p.133 ~ p.135
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Cheilitis Granulomatosa Successfully Treated with Minocycline
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Kim Hyo-Jin
Kang Jeong-Nan
Park In-Ho
Jung So-Young
Seol Jung-Eun
Sung Ho-Suk
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Abstract
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Cheilitis granulomatosa, a rare disease of unknown cause, is characterized clinically by recurrent or persistent swelling of the lip. Histopathologically, the dermis contains non-necrotizing granuloma, lymphangiectasia, and perivascular lymphocytic infiltration. Treatment of cheilitis granulomatosa is difficult, due to its unknown etiology. Several therapeutic methods have been attempted, including systemic and intralesional corticosteroids, oral metronidazole, non-steroidal anti-inflammatory drugs (NSAIDs), hydroxychloroquine, and surgical reduction, but unfortunately no treatment method has yet proven reliable.
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KEYWORD
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Cheilitis granulomatosa, Minocycline
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